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Two-Staged Transcatheter Aortic Valve Replacement in Severely Calcified Sinotubular Junction
Shivani Bhat1, Chase J Ellingson2, Jyotpal Singh3
1Prairie Vascular Research Inc, Regina, Canada; College of Medicine, University of Saskatchewan, Regina, Canada; Saskatchewan Health Authority (SHA), Saskatoon, Canada.
JACC. Case Reports
|April 2, 2026
Summary
A novel two-stage balloon inflation technique improves transcatheter aortic valve implantation safety in patients with severe sinotubular junction calcification. This method enhances valve anchoring and minimizes stress on the aortic root.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Severe sinotubular junction (STJ) calcification poses significant risks during transcatheter aortic valve implantation (TAVI).
- These risks include aortic dissection, root rupture, and improper valve placement.
- Current TAVI techniques may struggle with the anatomical challenges presented by STJ calcification.

