Body Composition of Preschool Children Born Term Versus Late-Preterm: A Follow-Up Study of Two Birth Cohorts

Dilip Kumar1, Priyanka Gupta2, Brijesh Kumar2

  • 1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Indian Pediatrics
|April 2, 2026
PubMed

Insights

Late-preterm born children had lower birth measurements but comparable body composition by preschool age. This study tracked body composition differences between term and late-preterm children.

Area of Science:

  • Pediatrics
  • Human Growth and Development
  • Nutritional Science

Background:

  • Late-preterm birth (34-36 weeks gestation) is common and may impact long-term health.
  • Body composition differences established at birth may persist or resolve during early childhood.

Purpose of the Study:

  • To compare the body composition of term-born versus late-preterm-born children at preschool age (3-5 years).

Main Methods:

  • Assessed anthropometry, fat mass (FM), FM%, fat mass index (FMI), fat-free mass (FFM), and fat-free mass index (FFMI) using air displacement plethysmography.
  • Included 3-5-year-old children from term and late-preterm birth cohorts, excluding those with chronic illness or neurodevelopmental disability.
  • Ensured all included children were appropriate for gestational age.

Main Results:

  • At birth, late-preterm infants had lower FM, FFM, FMI, and FFMI compared to term-born infants.
  • At preschool age, height-for-age Z-score, BMI-for-age Z-score, FM%, and FFMI were comparable between the two groups.
  • The change in weight-for-age Z-score from birth to preschool age positively correlated with FM% in both groups.

Conclusions:

  • While late-preterm children were smaller with lower FMI and FFMI at birth, their anthropometric parameters and body composition were similar to term-born children by preschool age.
  • This suggests catch-up growth in body composition occurs for late-preterm infants by 3-5 years of age.
Abstract

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