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Updated: Apr 4, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Endoscopic Suture Ligation and Sclerotherapy for Pharyngolaryngeal Venous Malformation
Jiajun Tian1, Juke Ma1, Ahmad A Hariri2
1Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, Shandong, China.
Objective:
Pharyngolaryngeal venous malformations (VMs) can cause airway obstruction and bleeding. This study evaluates the effectiveness of suture ligation combined with sclerotherapy for VM management.
Methods:
We retrospectively analyzed 53 patients with pharyngolaryngeal VMs treated between January 2017 and September 2024. Preoperative evaluation included fibreoptic laryngoscopy and imaging. Suture ligation aimed to transfix and obstruct the VM, followed by intralesional bleomycin injection.
Results:
The study included 23 males and 30 females (mean age 50.19 years). Most cases (71.7%) were solitary lesions. A single procedure achieved complete VM resolution in 79.25% of patients, with only one case showing minimal (less than 50%) reduction. Reoperation achieved complete regression in an additional 16.98% (nine cases). No prophylactic or emergent tracheostomy was necessary. One patient had a pre-existing tracheostomy. No serious postoperative complications occurred.
Conclusion:
Suture ligation combined with sclerotherapy offers a safe, minimally invasive, and effective approach for treating pharyngolaryngeal VMs. This technique achieves high success rates with minimal complications, promoting patient satisfaction.
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