Related Experiment Video

Updated: Apr 4, 2026

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
15:33

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation

Published on: August 13, 2013

16.5K

Retroviral Transduction of Human CD4+ T Cells with Membrane-Attached IL-10 Generates Type 1-Like Regulatory T Cells

Dayana Blokon-Kogan1,2, Shaul Davidson1, Maya Levi-Mann1

  • 1Laboratory of Cellular Immunotherapy & Synthetic Biology, MIGAL - Galilee Research Institute, Kiryat Shmona, Israel.

Human Gene Therapy
|April 3, 2026
PubMed

Keywords:
CD4+ T cellsCD49bLAG-3Tr1 cellsmagnetic beads purificationmembrane-attached IL-10retroviral transduction

More Related Videos

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function11:50

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Published on: November 4, 2016

11.7K
Retroviral Transduction of T-cell Receptors in Mouse T-cells10:14

Retroviral Transduction of T-cell Receptors in Mouse T-cells

Published on: October 22, 2010

36.3K

Related Concept Videos

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
3.3K
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
17.4K