Risk Factors for Upper Urinary Tract Stone Recurrence: A Retrospective Study of 247 Patients

Area of Science:

• Urology
• Nephrology
• Clinical Chemistry

Background:

• Urolithiasis presents high incidence and recurrence rates, posing a significant disease burden.
• Minimally invasive treatments like ureteroscopic lithotripsy are common, yet recurrence remains a challenge.

Purpose of the Study:

• To identify laboratory and demographic risk factors for upper urinary tract stone recurrence within three years.
• To evaluate associations between patient data and stone recurrence post-surgical treatment.

Main Methods:

• Retrospective analysis of 247 patients treated for upper urinary tract stones.
• Collected data included demographics, medical history, blood, and urine test results.
• Multivariate logistic regression identified significant risk factors for recurrence.

Main Results:

• A low C-reactive protein albumin lymphocyte (CALLY) index was associated with increased stone recurrence.
• Elevated serum creatinine levels were identified as a significant risk factor for recurrence.
• These factors were significant in multivariate logistic regression analysis (P<0.05).

Conclusions:

• Patients with a low CALLY index and high serum creatinine are at higher risk of upper urinary tract stone recurrence within three years.
• These laboratory markers can aid in predicting recurrence risk in patients undergoing initial surgical treatment.