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Exploring Non-pharmacological Hypertension Management: DASH, Paleolithic, and Ketogenic Diet Comparisons: A
Pranay Wal1, Deepankar Rath2, Neha Verma1
1PSIT-Pranveer Singh Institute Of Technology(Pharmacy), Pharmacy, NH 19 Kanpur Agra Highway BhautiKanpur, India.
Current Hypertension Reviews
|April 3, 2026
Summary
Dietary interventions like the DASH and Paleolithic diets significantly reduce blood pressure and improve metabolic health in hypertension management. These sustainable strategies offer promising results, but long-term adherence and personalization are key for optimal outcomes.
Area of Science:
- Cardiology
- Nutrition Science
- Public Health
Background:
- Hypertension affects over one-third of adults globally, contributing significantly to premature mortality.
- Pharmaceutical interventions have advanced, yet dietary strategies are increasingly recognized for hypertension prevention and management.
Purpose of the Study:
- To systematically review the impact of four dietary strategies—DASH, Paleolithic, low-carbohydrate, and ketogenic diets—on hypertension.
- To evaluate the effectiveness of these diets in reducing blood pressure and improving cardiovascular risk.
Main Methods:
- A systematic review adhering to PRISMA 2020 guidelines.
- Literature search of PubMed, MEDLINE, and Cochrane databases (1995-2025) using keywords: Hypertension, DASH Diet, Paleolithic Diet, Ketogenic Diet, Low-Carbohydrate Diet, Blood Pressure, Cardiovascular Risk.
- Independent screening of titles and abstracts by two investigators.
Main Results:
- Thirteen studies involving 87,597 individuals were analyzed.
- The DASH diet consistently lowered systolic blood pressure in adults.
- Paleolithic, low-carbohydrate, and ketogenic diets improved blood pressure and weight in overweight individuals.
- The Paleolithic diet showed significant benefits for blood pressure and metabolic health.
Conclusions:
- Dietary interventions are effective, sustainable strategies for hypertension management.
- The DASH and Paleolithic diets demonstrate the strongest evidence for reducing blood pressure and cardiometabolic risk.
- Long-term safety, compliance, personalization, and lifestyle integration are crucial for optimizing outcomes.
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