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Anaphylaxis: Clinical Criteria, Severity, and Clinical Courses

Timothy E Dribin1

  • 1Division of Emergency Medicine, Cincinnati Children's Hospital Medical Center, 3244 Burnet Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

Immunology and Allergy Clinics of North America
|April 3, 2026
PubMed
Summary

Anaphylaxis diagnosis can be uncertain, lacking a gold-standard test. The new 2024 Anaphylaxis Clinical Support Tool aims to resolve discrepancies in current diagnostic criteria for this severe allergic reaction.

Keywords:
Acute allergic reactionsAnaphylaxisBiphasic anaphylaxisEmergency departmentEpinephrinePersistent anaphylaxisRefractory anaphylaxisSeverity grading

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