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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Related Experiment Video

Updated: Apr 5, 2026

Transplantation of Pulmonary Valve Using a Mouse Model of Heterotopic Heart Transplantation
10:56

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Published on: July 23, 2014

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Pediatric heart transplantation.

Jonathan N Johnson1,2, Steven J Kindel1, Rebecca K Ameduri1

  • 1Department of Pediatrics/Division of Pediatric Cardiology, Mayo Clinic Children's.

Current Opinion in Organ Transplantation
|April 4, 2026
PubMed
Summary
This summary is machine-generated.

Pediatric heart transplantation faces ongoing challenges, primarily donor organ scarcity. Advances in registries and networks aid collaboration, while xenotransplantation offers future hope for pediatric heart recipients.

Keywords:
organ donationpediatric heart transplantationpsychosocial evaluationxenotransplantation

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Area of Science:

  • Pediatric Cardiology
  • Transplantation Medicine
  • Immunology

Background:

  • Pediatric heart transplantation is a critical treatment for end-stage heart failure in children.
  • Significant advancements have improved outcomes, yet substantial hurdles persist.

Purpose of the Study:

  • To review key research published in pediatric heart transplantation over the past year.
  • To highlight current challenges and future directions in the field.

Main Methods:

  • Literature review of recent publications in pediatric heart transplantation.
  • Synthesis of findings related to donor availability, collaborative networks, psychosocial evaluations, and emerging technologies.

Main Results:

  • Donor organ scarcity remains a primary obstacle, necessitating efforts to increase donor numbers and organ quality.
  • Collaborative initiatives like the Pediatric Heart Transplant Society (PHTS) and Advanced Cardiac Therapies Improving Outcomes Network (ACTION) enhance multisite collaboration.
  • A consensus framework for psychosocial evaluations aids in managing scarce resources.
  • Xenotransplantation is emerging as a potentially transformative advancement.

Conclusions:

  • Addressing donor availability and organ scarcity is paramount for pediatric heart transplantation.
  • Continued progress in collaborative efforts and preparation for innovations like xenotransplantation are crucial.