Jove
Visualize
Contact Us

Related Concept Videos

CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

1.6K
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Unrolling worms: Genome Editing to Rewrite Roller Phenotypes in <i>C. elegans</i>.

microPublication biology·2026
Same journal

Ubiquitin-elongating enzyme Ufd2 confers resistance to hygromycin B in <i>Saccharomyces cerevisiae</i>.

microPublication biology·2026
Same journal

<i>Caenorhabditis elegans</i> H1 histone variant HIL-2 is positively regulated by nutrient availability and insulin/IGF signaling but does not affect development.

microPublication biology·2026
Same journal

RNAi of the electron transport chain <i>ATPsynβL</i> in glutamate neurons protects against age-related intestinal barrier dysfunction.

microPublication biology·2026
Same journal

Timing matters: Rhizobia strain rankings based on host biomass shift between early and late harvests.

microPublication biology·2026
Same journal

Cryo-electron tomography reveals OmpB is required for the <i>Rickettsia</i> <i>parkeri</i> S-layer.

microPublication biology·2026
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Apr 7, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.7K

Diet Modification Alters Repeated Exposure Ethanol Tolerance Development.

Enrique Rodriguez Borrero1, Laura Jimenez Marrero1, Priscilla Gutierrez Ortiz1

  • 1Biology, University of Puerto Rico at Cayey, Cayey, PR.

Micropublication Biology
|April 6, 2026
PubMed
Summary

Diet significantly impacts alcohol tolerance. High-fat diets disrupt ethanol tolerance development in fruit flies, while high-protein diets enhance repeated tolerance, highlighting diet

More Related Videos

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
15:27

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development

Published on: July 13, 2014

15.3K
A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats
13:24

A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats

Published on: September 19, 2014

13.4K

Related Experiment Videos

Last Updated: Apr 7, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
05:12

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder

Published on: June 23, 2023

1.7K
Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
15:27

Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development

Published on: July 13, 2014

15.3K
A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats
13:24

A Procedure to Observe Context-induced Renewal of Pavlovian-conditioned Alcohol-seeking Behavior in Rats

Published on: September 19, 2014

13.4K

Area of Science:

  • Neuroscience
  • Behavioral Science
  • Nutritional Science

Background:

  • Diet is a key environmental factor affecting alcohol-related behaviors.
  • The specific influence of diet on the development of ethanol tolerance is not fully understood.

Purpose of the Study:

  • To investigate how high-protein and high-fat diets modulate the development of rapid and repeated ethanol tolerance.
  • To examine the effects of dietary modifications on ethanol sensitivity and neuroadaptive responses in Drosophila melanogaster.

Main Methods:

  • Utilized a repeated-exposure sedation assay in Drosophila melanogaster.
  • Compared ethanol tolerance development in flies fed standard, high-protein, and high-fat diets.

Main Results:

  • Flies on a standard diet developed both rapid and repeated ethanol tolerance.
  • High-protein diets enhanced the acquisition of repeated ethanol tolerance.
  • High-fat diets reduced survival, abolished rapid tolerance, and limited repeated tolerance development.

Conclusions:

  • Diet composition differentially influences ethanol sensitivity and tolerance.
  • High-fat feeding significantly disrupts ethanol-induced neuroadaptive responses in Drosophila.