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18 F-FDG PET/CT Findings in Fahr Syndrome : A Case Report
Fernando López-Bermejo García1, José Carlos Rodríguez Gómez, Javier Gatón Ramírez
1Department of Nuclear Medicine, University General Hospital of Ciudad Real, Ciudad Real, Spain.
Clinical Nuclear Medicine
|April 6, 2026
Summary
This case highlights Fahr syndrome, a rare neurological disorder, in an 80-year-old woman. Characteristic 18F-FDG PET/CT imaging findings are presented to assess cognitive decline.
Area of Science:
- Neurology
- Radiology
- Nuclear Medicine
Background:
- Fahr syndrome is a rare neurological disorder characterized by abnormal calcification in the brain.
- Patients may present with cognitive decline, memory loss, and impulse control issues.
Purpose of the Study:
- To illustrate the characteristic 18F-FDG PET/CT imaging findings in a patient with Fahr syndrome.
- To correlate imaging findings with clinical presentation of cognitive deterioration.
Main Methods:
- Case presentation of an 80-year-old woman with cognitive decline.
- Brain CT scan to identify intracranial calcifications consistent with Fahr syndrome.
- 18F-FDG PET/CT imaging to assess cerebral metabolic activity and cognitive function.
Main Results:
- Brain CT revealed findings indicative of Fahr syndrome.
- 18F-FDG PET/CT demonstrated specific patterns of reduced glucose metabolism associated with cognitive impairment.
Conclusions:
- 18F-FDG PET/CT is a valuable tool for assessing cognitive deterioration in Fahr syndrome.
- This case underscores the characteristic imaging features of this rare neurological condition.
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