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Clinical efficacy of neuromodulation in isolated dystonia: A systematic review of motor function improvement

Diamante Carta1, Viviana Lo Buono2, Laura Culicetto1

  • 1IRCCS Centro Neurolesi "Bonino Pulejo", S.S. 113 Via Palermo C/da Casazza, Messina, 98123, Italy.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|April 6, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Deep brain stimulationDystoniaGPiMRgFUSMotor improvementNon-invasive neuromodulationQuetsiSTNTranscranial magnetic stimulationtDCS

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Alterations in Muscle Tone ll01:12

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Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
Alterations in Muscle Tone lll01:11

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Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...

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