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Calcium Carbonate Formation in the Presence of Biopolymeric Additives
Published on: May 14, 2019
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Trends and Future Perspectives in Additive Modifications of Calcium Silicate-Based Cements: A Scoping Review
Kenta Tsuchiya1,2, Salvatore Sauro2, Jukka P Matinlinna3,4
1Department of Restorative Dentistry and Endodontics, Hokkaido University, Sapporo, Japan.
Summary
This review of calcium silicate-based cements (CSCs) shows modifications focus on setting time, biocompatibility, and antibacterial properties. Current additive strategies are insufficient, highlighting a need for integrated design in dental materials.
Area of Science:
- Biomaterials Science
- Dental Materials Research
- Nanotechnology in Medicine
Background:
- Calcium silicate-based cements (CSCs) are widely used in dentistry.
- Modifications aim to improve their clinical performance.
- Understanding additive effects is crucial for optimizing CSCs.
Purpose of the Study:
- To identify commonly modified commercial CSCs.
- To evaluate trends in additive-property relationships.
- To highlight research gaps for clinical applications.
Main Methods:
- Scoping review of laboratory studies (2015-2024).
- Searches in PubMed, ScienceDirect, and Web of Science.
- Analysis of 51 studies meeting inclusion criteria.
Main Results:
- ProRoot was the most studied CSC.
- Additives primarily targeted setting time, biocompatibility, antibacterial properties, and osteogenic differentiation.
- Observed a shift from bioactivity to physicochemical optimization.
- Metals and fluorides enhanced antibacterial properties; phosphates and bioactive compounds improved biocompatibility and osteogenesis; calcium chloride accelerated setting.
- Distinct additive category-property associations were identified.
Conclusions:
- Single-category additive strategies are insufficient for CSC optimization.
- Several CSC properties remain underexplored.
- Integrative CSC design is needed for enhanced clinical application.
Keywords:
additivecalcium silicate cementendodonticsmineral trioxide aggregatemodified MTAscoping reviewMore Related Videos
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