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Updated: Apr 8, 2026

Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
An emerging family of immunogenic epitopes in Chagas disease
Christopher Markosian1, Ricardo J Giordano2, Renata Pasqualini1
1Rutgers Cancer Institute, Newark, NJ, USA; Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ, USA.
Abstract:
Kortbawi et al. identified trans-sialidase 23 (TS23) via phage display as an immunodominant B-cell epitope of Trypanosoma cruzi trans-sialidases, broadly detected serologically in Chagas-endemic regions. Independent mapping confirmed this antigenic landscape. TS23, FLY, and TS9 may define an emerging family of immunogenic epitopes with implications for tissue tropism and translational applications.
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