Upper Jaw Mucormycosis in an Immunocompetent Patient: A Clinical Report

Chloé Thepenier1, Adélaïde Carlier1, Louis Brochet1

  • 1Maxillofacial Surgery Department, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France, chu-lyon.fr.

Insights

Mucormycosis, a severe fungal infection, is rising post-COVID-19. This case shows an immunocompetent patient recovering with minimal intervention, questioning standard extensive debridement protocols.

Area of Science:

  • Infectious Diseases
  • Ophthalmology
  • Otolaryngology

Background:

  • Mucormycosis is a severe opportunistic infection with increasing incidence, particularly since the COVID-19 pandemic.
  • It typically affects immunocompromised individuals, including those with diabetes or on corticosteroids.
  • Standard treatment involves aggressive surgical debridement and lengthy antifungal therapy.

Purpose of the Study:

  • To report a case of maxillary mucormycosis in an immunocompetent patient following COVID-19.
  • To evaluate the efficacy of conservative management in such cases.
  • To question the necessity of extensive debridement in immunocompetent patients without risk factors.

Main Methods:

  • Case report of an immunocompetent patient with maxillary mucormycosis.
  • Clinical presentation and diagnostic workup described.
  • Treatment approach involving minimal debridement and antifungal therapy detailed.

Main Results:

  • The patient, despite being immunocompetent and having no other risk factors, developed maxillary mucormycosis associated with COVID-19.
  • The condition responded well to limited surgical debridement and antifungal medication.
  • No recurrence or significant complications were observed post-treatment.

Conclusions:

  • Maxillary mucormycosis can occur in immunocompetent individuals post-COVID-19.
  • Conservative management may be sufficient in select immunocompetent patients.
  • This case challenges the universal application of extensive debridement for mucormycosis.

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