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Upper Jaw Mucormycosis in an Immunocompetent Patient: A Clinical Report
Chloé Thepenier1, Adélaïde Carlier1, Louis Brochet1
1Maxillofacial Surgery Department, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France, chu-lyon.fr.
Abstract:
Mucormycosis is a rare but severe opportunistic infection, whose incidence has substantially increased since the coronavirus disease 2019 (COVID-19) pandemic. It predominantly affects immunocompromised patients, individuals with diabetes, and those receiving corticosteroids. Standard treatment involves extensive debridement of affected tissue combined with prolonged antifungal therapy. We present a case of an immunocompetent patient with no identifiable risk factors who developed maxillary mucormycosis associated with COVID-19 illness. The condition responded favorably to minimal debridement and antifungal treatment. This case raises questions about the need for extensive debridement in immunocompetent patients without underlying risk factors.
Insights
Mucormycosis, a severe fungal infection, is rising post-COVID-19. This case shows an immunocompetent patient recovering with minimal intervention, questioning standard extensive debridement protocols.
Area of Science:
- Infectious Diseases
- Ophthalmology
- Otolaryngology
Background:
- Mucormycosis is a severe opportunistic infection with increasing incidence, particularly since the COVID-19 pandemic.
- It typically affects immunocompromised individuals, including those with diabetes or on corticosteroids.
- Standard treatment involves aggressive surgical debridement and lengthy antifungal therapy.
Purpose of the Study:
- To report a case of maxillary mucormycosis in an immunocompetent patient following COVID-19.
- To evaluate the efficacy of conservative management in such cases.
- To question the necessity of extensive debridement in immunocompetent patients without risk factors.
Main Methods:
- Case report of an immunocompetent patient with maxillary mucormycosis.
- Clinical presentation and diagnostic workup described.
- Treatment approach involving minimal debridement and antifungal therapy detailed.
Main Results:
- The patient, despite being immunocompetent and having no other risk factors, developed maxillary mucormycosis associated with COVID-19.
- The condition responded well to limited surgical debridement and antifungal medication.
- No recurrence or significant complications were observed post-treatment.
Conclusions:
- Maxillary mucormycosis can occur in immunocompetent individuals post-COVID-19.
- Conservative management may be sufficient in select immunocompetent patients.
- This case challenges the universal application of extensive debridement for mucormycosis.
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