Bacterial bioactive groups for the improved and stable functionality of nanoparticles for biomedical application

Area of Science:

• Biotechnology
• Nanotechnology
• Microbiology

Background:

• Metal nanoparticles (NPs) are crucial for biomedical applications.
• Green synthesis using nanotechnology offers a sustainable approach for NP fabrication.
• Bacterial bioactive molecules play a significant role in biosynthesis.

Purpose of the Study:

• To review recent progress in bacterial biosynthesis of metal NPs.
• To elucidate the role of microbial metabolites in NP synthesis.
• To highlight the biomedical potential of biosynthesized metal NPs.

Main Methods:

• Discussion of bacterial bioactive functional molecules involved in NP biosynthesis.
• Presentation of NP synthesis cascades using biological metabolites (enzymes, proteins, exopolysaccharides).
• Elucidation of mechanisms for synthesizing various metal NPs (Ag, Au, Zn, Cu, magnetite, Pd).

Main Results:

• Bacterial metabolites act as reducing and stabilizing agents in NP synthesis.
• Microbial metabolites harmonize the biosynthetic process for metal NPs.
• Diverse metal NPs can be synthesized using bacterial approaches.

Conclusions:

• Bacterial biosynthesis offers a green and efficient route for producing metal NPs.
• Microbial metabolites are integral to the controlled synthesis of NPs.
• Biosynthesized metal NPs hold significant promise for future biomedical applications.