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Updated: Apr 10, 2026

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Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
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Reemerging and New Infectious Diseases.
1Department of Dermatology and Dermatologic Surgery, The Mehdical University of South Carolina, 135 Rutledge Avenue, 11th Floor, Charleston, SC, USA.
Dermatologic Clinics
|April 8, 2026
Summary
Reemerging infectious diseases like monkeypox are a growing global concern. Accurate diagnosis through laboratory confirmation is critical to distinguish these from herpetic infections.
Area of Science:
- Infectious Diseases
- Dermatology
- Public Health
Background:
- Reemerging infectious diseases present a significant global health challenge.
- Infections such as monkeypox and syphilis are resurfacing with altered clinical presentations and wider geographic distribution.
- Surveillance indicates that some suspected cases may be misdiagnosed.
Purpose of the Study:
- To highlight the diagnostic challenges posed by reemerging infectious diseases.
- To emphasize the importance of laboratory confirmation in differentiating similar-presenting conditions.
- To address the potential misdiagnosis of herpetic lesions as other infectious diseases.
Main Methods:
- Review of surveillance data regarding infectious disease outbreaks.
- Analysis of clinical presentations of suspected cases.
- Emphasis on histopathologic and laboratory diagnostic techniques.
Main Results:
- A notable proportion of suspected cases exhibit umbilicated lesions characteristic of herpetic infections.
- Clinical patterns and geographic spread of diseases like monkeypox are evolving.
- Laboratory confirmation is essential for accurate diagnosis.
Conclusions:
- Distinguishing between reemerging infectious diseases and herpetic infections requires careful clinical evaluation.
- Histopathologic and laboratory confirmation are crucial for accurate diagnosis and effective public health management.
- The rise in reemerging diseases necessitates enhanced diagnostic strategies and surveillance.
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