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Richard Tecwyn Williams - the Birmingham years (1934-1942)
Steve Mitchell1, Rosemary Waring2
1Faculty of Medicine, Imperial College London, UK.
Abstract:
Richard Tecwyn Williams is acclaimed for being amongst the founders of the systematic study of foreign compound metabolism. His chemically-oriented collation of peripheral and often unappreciated metabolic observations, together with his own researches, helped to engineer a new field of study.Although researchers travel along a pathway, inevitable interaction with colleagues, unique circumstances and unforeseen opportunities will buffet the journey until a suitable niche appears. A vocation emerges, drawn out as it may be but nevertheless, dictating the future direction. This sequence was to occur during Williams' time at Birmingham University.At Birmingham, Williams entered a transitional period in his scientific career. From initially continuing his work on glucuronic acid, he progressed through phenols and various monoterpenes to the metabolism of sulphonamides, slowly changing his initial focus on conjugating agents themselves to their broader role in the metabolic fate of xenobiotics.
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