Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

3.3K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
3.3K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

3.4K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.4K
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

4.2K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
4.2K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

5.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
5.2K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

2.2K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
2.2K
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

4.1K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasma exosome-derived miRNA-887-5p alleviates high glucose- and lipid-induced endothelial cell dysfunction.

Nutrition & diabetes·2026
Same author

Multimodal multitask deep learning for grading management system in non-small cell lung cancer.

Nature communications·2026
Same author

CLINT1 is a subtype-specific biomarker and a downstream effector of p53-R273H in lung adenocarcinoma migration.

Acta biochimica et biophysica Sinica·2026
Same author

Anlotinib for Advanced Peritoneal Follicular Dendritic Cell Sarcoma: A Case Report and Literature Revie.

Current cancer drug targets·2026
Same author

TMEM72 Inhibits the proliferation by promoting cellular senescence through the activation of the P38/MAPK signaling pathway in renal cell carcinoma.

Translational oncology·2026
Same author

Late diagnosis and effective everolimus treatment in a familial case of tuberous sclerosis complex: a case report.

Frontiers in genetics·2026
Same journal

Structural Validity and Factorial Analysis of the Brazilian Oral Health Impact Profile for Temporomandibular Disorders Instrument.

Oral diseases·2026
Same journal

Effects of Pistacia lentiscus Leaf-Twig and Resin (Mastic) Oils on Salivary Flow in Healthy Individuals.

Oral diseases·2026
Same journal

Oral Delivery of Bioencapsulated CTB-Pro-IGF-1 Enhances Bone Regeneration in a Pre-Clinical Rat Model of Jaw Osteoradionecrosis.

Oral diseases·2026
Same journal

Trends in Stage and Age at Diagnosis of Oral Squamous Cell Carcinoma Over Time: A Systematic Review and Meta-Analysis.

Oral diseases·2026
Same journal

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders.

Oral diseases·2026
Same journal

Authors' Reply "Synchronous Soft-Tissue Lesions in the Oral Cavity in an Adolescent".

Oral diseases·2026
See all related articles

Related Experiment Video

Updated: Apr 10, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

12.5K

Association Between Periodontitis and COPD: A Large Multi-Database Cross-Sectional Study.

Hongkai Zhang1,2,3,4, Guoping Cheng1,2,3, Lingling Ye5

  • 1Center of Stomatology, the Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, China.

Oral Diseases
|April 8, 2026
PubMed
Summary
This summary is machine-generated.

Periodontitis increases the risk of chronic obstructive pulmonary disease (COPD), and COPD independently elevates periodontitis severity. Both conditions share similar systemic inflammation markers, indicating a bidirectional link.

Keywords:
COPDNHANESperiodontitissystemic inflammation

More Related Videos

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar
07:14

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar

Published on: May 30, 2025

1.2K

Related Experiment Videos

Last Updated: Apr 10, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

12.5K
Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar
07:14

Murine Model of Advanced Periodontitis Induced by Nylon Ligature in the Second Upper Molar

Published on: May 30, 2025

1.2K

Area of Science:

  • Oral health and respiratory medicine
  • Inflammatory diseases
  • Public health

Background:

  • Periodontitis is a chronic inflammatory disease initiated by bacteria.
  • Chronic obstructive pulmonary disease (COPD) is a major global health concern.
  • The association between periodontitis and COPD requires further investigation.

Purpose of the Study:

  • To investigate the bidirectional association between periodontitis and COPD.
  • To compare systemic inflammation markers in patients with periodontitis and COPD.

Main Methods:

  • Analysis of NHANES 2009-2014 data (n=3626) using multivariable logistic and ordinal regression.
  • Comparison of systemic inflammation markers (NLR, PLR, MLR, SII, AISI) using local clinical data (n=210).

Main Results:

  • Mild-moderate and severe periodontitis were associated with increased COPD risk (OR=1.44 and 1.52).
  • COPD was an independent risk factor for periodontitis severity (OR=1.44).
  • Elevated AISI, SII, NLR, and MLR were observed in both periodontitis and COPD groups compared to controls.

Conclusions:

  • Periodontitis and COPD exhibit a robust, independent, bidirectional association.
  • Both conditions share a similar systemic inflammatory profile.