Case Report: Intrahepatic cholangiocarcinoma masquerading as a giant hepatic cyst

Even asymptomatic giant hepatic cysts may harbor malignancy. Intraductal papillary carcinoma (IPC) of the liver, a histologic subtype of intrahepatic cholangiocarcinoma (ICC), is relatively uncommon among primary hepatic malignancies. The coexistence of ICC with hepatic cysts is exceedingly rare and often leads to misdiagnosis or missed diagnosis. This case report describes a patient in whom both ICC and a giant hepatic cyst were identified during a routine physical examination. Initial imaging favored a diagnosis of a giant hepatic cyst. Laparoscopic hepatic cystectomy with partial hepatectomy was performed, and histopathologic examination confirmed intraductal papillary carcinoma.