Related Experiment Video
Updated: Apr 10, 2026

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Electrophotochemical Decarboxylative C-H Fluoroalkylation via a Fe2O3-FTO Active Photoanode
Vladimir Motornov1, Zhi Liu1, Kentaro Imaoka2
1Wöhler Research Institute for Sustainable Chemistry (WISCh), Georg-August-Universität Göttingen, Tammannstraße 2, 37077 Göttingen, Germany.
None:
C-H fluoroalkylation of heteroarenes and biomolecules employing inexpensive carboxylic acids based on electrophotochemical oxidation on a Fe2O3 photoanode was developed. Notably, the devised approach proved amenable to a wide range of versatile late-stage C-H fluoroalkylations of biorelevant heterocycles. Mechanistic studies supported a direct electron transfer to form a fluoroalkyl radical with a cost-efficient heterogeneous iron catalyst.
More Related Videos
10:21Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions
Published on: October 5, 2019
09:17Reductive Electropolymerization of a Vinyl-containing Poly-pyridyl Complex on Glassy Carbon and Fluorine-doped Tin Oxide Electrodes
Published on: January 30, 2015
Related Concept Videos
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Thermal and Photochemical Electrocyclic Reactions: Overview
Cycloaddition Reactions: MO Requirements for Photochemical Activation
Thermal Electrocyclic Reactions: Stereochemistry
Selection Rules: Thermal Activation
Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
Electrophilic Aromatic Substitution: Fluorination and Iodination of Benzene
Electrophilic Aromatic Substitution: Friedel–Crafts Acylation of Benzene