Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pneumonia II: Pathophysiology

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Other Pulmonary Disorders

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Pneumonia I: Introduction

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ayurveda in Contemporary Healthcare: A Narrative Overview of Select Therapeutic Interventions and Their Emerging Clinical and Mechanistic Perspectives.

Cureus·2026

Same author

A Systematic Review of Herbal Medicines in the Management of Diabetes: Efficacy, Toxicological Profiles, and Clinical Safety Considerations.

Cureus·2026

Same author

Comparative Analysis of Clinical Outcomes in Patients With Type 2 Diabetes Mellitus on Monotherapy Versus Combination Therapy.

Cureus·2026

Same author

Integrated Management Strategies for Diabetes Mellitus and Hypertension: A Systematic Review.

Cureus·2026

Search research articles

Related Experiment Video

Updated: Apr 11, 2026

Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection

Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection

Published on: September 19, 2025

Pathological lung tissue changes in common infectious diseases.

Amit Nampalliwar¹, Sachin Pundlikrao Ambirwar², Swati Narayan Khandale³

¹Department of Pathology (Roga Nidan & Vikriti Vigyana), Government Ayurved College & Hospital, Bilaspur (C.G.), Chhattisgarh, India.

|April 10, 2026

Summary

Histopathology of infectious lung diseases reveals distinct patterns. Microscopic examination aids in diagnosing bacterial, viral, fungal, and tuberculous infections, correlating with patient outcomes.

Keywords:

Infectious lung diseases fungal infections histopathology pneumonia tuberculosis viral pneumonia

More Related Videos

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Related Experiment Videos

Last Updated: Apr 11, 2026

Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection

Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection

Published on: September 19, 2025

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Visualizing Lung Cellular Adaptations during Combined Ozone and LPS Induced Murine Acute Lung Injury

Published on: March 21, 2021

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Area of Science:

Pulmonary Medicine
Pathology
Infectious Diseases

Background:

Infectious lung diseases are significant causes of global morbidity and mortality.
Accurate diagnosis frequently depends on identifying specific histopathological patterns.

Purpose of the Study:

To compare the histopathological changes associated with different infectious etiologies of the lung.
To evaluate the diagnostic and prognostic value of microscopic examination in infectious lung diseases.

Main Methods:

Retrospective observational study of 90 archived lung specimens (biopsy, resection, autopsy).
Analysis of pathological changes related to bacterial, viral, fungal, and tuberculous infections.

Main Results:

Bacterial infections were most common, showing acute inflammation and consolidation.
Tuberculosis and fungal infections presented with granulomatous inflammation and caseous necrosis.
Viral infections were characterized by alveolar damage.

Conclusions:

Distinct histopathological profiles correlate with specific infectious lung disease causes.
Microscopic examination is crucial for diagnosis and prognosis in infectious lung diseases.