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Pathological lung tissue changes in common infectious diseases

Amit Nampalliwar1, Sachin Pundlikrao Ambirwar2, Swati Narayan Khandale3

  • 1Department of Pathology (Roga Nidan & Vikriti Vigyana), Government Ayurved College & Hospital, Bilaspur (C.G.), Chhattisgarh, India.

Bioinformation
|April 10, 2026
PubMed

Insights

Histopathology of infectious lung diseases reveals distinct patterns. Microscopic examination aids in diagnosing bacterial, viral, fungal, and tuberculous infections, correlating with patient outcomes.

Area of Science:

  • Pulmonary Medicine
  • Pathology
  • Infectious Diseases

Background:

  • Infectious lung diseases are significant causes of global morbidity and mortality.
  • Accurate diagnosis frequently depends on identifying specific histopathological patterns.

Purpose of the Study:

  • To compare the histopathological changes associated with different infectious etiologies of the lung.
  • To evaluate the diagnostic and prognostic value of microscopic examination in infectious lung diseases.

Main Methods:

  • Retrospective observational study of 90 archived lung specimens (biopsy, resection, autopsy).
  • Analysis of pathological changes related to bacterial, viral, fungal, and tuberculous infections.

Main Results:

  • Bacterial infections were most common, showing acute inflammation and consolidation.
  • Tuberculosis and fungal infections presented with granulomatous inflammation and caseous necrosis.
  • Viral infections were characterized by alveolar damage.

Conclusions:

  • Distinct histopathological profiles correlate with specific infectious lung disease causes.
  • Microscopic examination is crucial for diagnosis and prognosis in infectious lung diseases.
Keywords:
Infectious lung diseasesfungal infectionshistopathologypneumoniatuberculosisviral pneumonia

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