Clinical evaluation of open flap debridement with or without Emdogain® in treating intrabony defects

Periodontitis causes intrabony defects and while open flap debridement (OFD) with EMD and GTR shows promise, the comparative effectiveness of EMD in treating these defects remains underexplored. Open flap debridement (OFD) or access flap surgery is used in conjunction with biological factors such as enamel matrix derivative (EMD) and regenerative techniques involving guided tissue regeneration (GTR) in order to overcome these intrabony defects. In numerous clinical investigations, the application of EMD has demonstrated notable clinical improvements in bone fill clinical attachment gain and pocket depth reduction. Thus, the clinical effectiveness of open flap debridement with and without enamel matrix derivative (EMD) in treating periodontal intrabony defects, further exploring EMD's contribution to clinical outcomes such as bone fill, attachment gain and pocket depth reduction is reported.