Refractory Atrial Tachycardia and Ivabradine in a Case of Catecholaminergic Polymorphic Ventricular Tachycardia
Hakan Küçüker1, Abdüsselam Genç2, Fahrettin Uysal1
1Department of Pediatric Cardiology, Bursa Uludag University, Faculty of Medicine, Bursa, Türkiye; Department of Translational Medicine, Bursa Uludag University, Institute of Health Sciences, Bursa, Türkiye.
Abstract:
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare hereditary arrhythmia characterized by adrenergic stress-induced polymorphic ventricular tachycardia. Supraventricular arrhythmias, including ectopic atrial tachycardia (EAT), may occur; however, their management in patients with CPVT has not been well established. This case report presents an 11-year-old boy with CPVT who developed drug-resistant EAT. Despite treatment with beta-blockers, flecainide, and sotalol, EAT persisted. Ivabradine therapy was initiated, resolving the arrhythmia within hours. This unique case highlights the potential role of ivabradine as a therapeutic option in carefully selected patients. Multicenter studies are required to further evaluate the potential role of ivabradine alongside beta-blockers in the management of CPVT-related arrhythmias.
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