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Related Experiment Video

Updated: Apr 12, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
06:04

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

717

Stroke Risk After TAVR: Balloon-Expandable vs Self-Expanding Valves in Community Practice.

Sant Kumar1, David Elison2, Ashish Pershad3

  • 1Creighton University School of Medicine, Phoenix, Arizona, USA; St. Joseph Hospital and Medical Center, Phoenix, Arizona, USA.

JACC. Advances
|April 10, 2026
PubMed
Summary
This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) valve type did not impact stroke risk within one year. Clinical factors like age and prior stroke history were the main predictors of stroke after TAVR.

Keywords:
TAVRballoon-expandable valveself-expanding valvestroke

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Health Services Research

Background:

  • Stroke is a significant complication following transcatheter aortic valve replacement (TAVR).
  • Limited contemporary data exists on stroke risk after TAVR in community hospital settings.
  • Understanding stroke risk factors is crucial for improving patient outcomes.

Purpose of the Study:

  • To investigate the association between different TAVR valve types and the risk of stroke within one year.
  • To analyze contemporary TAVR data from community practice to inform clinical decision-making.
  • To identify key predictors of stroke in patients undergoing TAVR.

Main Methods:

  • Analysis of 6,663 patients undergoing TAVR between January 2021 and February 2023.
  • Categorization of valves into balloon-expandable and self-expanding valve (SEV) types.
  • Utilized Kaplan-Meier methods and inverse probability of treatment weighting for robust statistical analysis.

Main Results:

  • No significant difference in 1-year stroke-free survival between balloon-expandable and self-expanding valves (P = 0.448).
  • Adjusted analysis confirmed no association between valve type and stroke risk (aHR: 1.54; P = 0.294).
  • Independent predictors of stroke included age, lower BMI, prior stroke, STS risk score, and alternative access.

Conclusions:

  • TAVR valve type is not a predictor of stroke within one year post-procedure.
  • Clinical variables such as age, STS risk score, and history of stroke are the primary drivers of stroke risk.
  • Focusing on patient-specific clinical factors is essential for stroke risk mitigation after TAVR.