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Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Ventilator-Associated Events: Surveillance and Prevention
Marie-Céline Zanella1, Chanu Rhee2, Michael Klompas2
1Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA; Infection Control Program and WHO Collaborating Centre, Faculty of Medicine, University of Geneva Hospitals, Geneva, Switzerland.
Ventilator-associated events (VAEs) are complications of mechanical ventilation linked to worse patient outcomes. Implementing VAE surveillance and specific care bundles can reduce VAE rates and improve patient safety.
Area of Science:
- Critical Care Medicine
- Pulmonary Medicine
- Infectious Disease Surveillance
Background:
- Mechanical ventilation is essential but carries risks of complications.
- Ventilator-associated events (VAEs) represent a spectrum of adverse outcomes during mechanical ventilation.
- Objective surveillance is needed to identify and mitigate these complications.
Purpose of the Study:
- To introduce the Ventilator-Associated Event (VAE) framework for surveillance.
- To highlight the clinical significance and impact of VAEs.
- To outline strategies for reducing VAE rates.
Main Methods:
- Utilizing an objective and reproducible surveillance framework for VAEs.
- Analyzing the association of VAEs with prolonged ventilation, ICU stay, and mortality.
- Reviewing interventions aimed at VAE reduction.
Main Results:
- VAEs are linked to increased mechanical ventilation duration, extended ICU stays, and higher mortality.
- VAE rates are reducible through targeted interventions.
- VAE surveillance serves as a valuable quality indicator.
Conclusions:
- The VAE framework offers objective surveillance for mechanical ventilation complications.
- Reducing VAEs can improve patient outcomes and enhance the safety of mechanical ventilation.
- VAE surveillance aids in risk identification, benchmarking, and quality improvement initiatives.
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