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New growth charts for children and adolescents in Catalonia, Spain: developed from routinely collected data
Núria Mora1, Anna Palomar-Cros2, Laura Pérez-Crespo2
1Primary Care Services Information System (SISAP), Institut Català de la Salut (ICS), Gran Via de les Corts Catalanes 587, Barcelona, Spain.
Insights
New growth charts for children in Catalonia, Spain, were developed using electronic health records. These region-specific charts, including weight and BMI, are higher in top percentiles than WHO standards, aiding early health condition detection.
Area of Science:
- Pediatrics
- Public Health
- Biostatistics
Background:
- Growth charts are critical for monitoring child development and identifying health issues early.
- Existing growth charts may not accurately reflect current population-specific growth patterns.
- Real-world data from electronic health records (EHR) offer a valuable resource for updating growth references.
Purpose of the Study:
- To develop updated, region-specific growth charts for children and adolescents in Catalonia, Spain.
- To utilize a large dataset from primary care EHR to create accurate anthropometric references.
- To provide healthcare professionals with a reliable tool for growth assessment in the local population.
Main Methods:
- Utilized routinely collected EHR data from Institut Català de la Salut (2013-2019).
- Included children aged 1 month to 14 years with birthweight >2500g and at least one anthropometric measurement.
- Employed Generalized Additive Models for Location, Scale and Shape (GAMLSS) to fit growth references for head circumference, weight, length/height, and BMI.
Main Results:
- Generated new growth charts based on 876,097 records from 155,950 children.
- New charts showed higher percentiles for weight and BMI (from age 4) compared to WHO standards.
- Validation confirmed chart accuracy, with minor differences in extreme percentiles for weight and BMI at older ages.
Conclusions:
- Successfully created novel, region-specific growth charts for Catalonia's pediatric population.
- The new charts accurately represent local growth patterns, offering an improvement over existing references.
- These charts serve as an essential tool for primary care professionals in Catalonia for growth monitoring.
Background:
Growth charts are essential for detecting early health conditions in children. This study aims to create up-to-date and region-specific growth charts for children and adolescents using large real-world data from primary care electronic health records (EHR) in Catalonia, Spain.
Methods:
We used routinely collected EHR of the Institut Català de la Salut, the main primary care provider in Catalonia. We included children aged one month to 14 years with a birthweight greater than 2500 gr, and at least one anthropometric measurement registered (2013-2019). Growth references for head circumference, weight, length/height, and body mass index (BMI) were fitted using GAMLSS models. We built our charts with data recorded in 2013, validated them using data from 2014 to 2019 and compared them to WHO and Spanish growth charts.
Results:
With a total of 876,097 records from 155,950 children, we estimated new growth charts. Our curves were higher in the highest percentile, especially for weight and BMI (starting from 4 years old), compared to the WHO standards and for extreme percentiles compared to outdated national charts but were similar to more recent national curves. Validation analyses showed similar results with differences only seen for extreme weight and BMI percentile curves, older ages and later years.
Conclusions:
We created new growth charts using a novel approach, accurately representing local growth patterns in the population living in Catalonia. These charts offer primary care professionals a valuable tool for assessing children's and adolescents' growth in the region.
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