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Risk Factors and Clinical Severity in Chronic Venous Disease: A New Look
Éva Badak1, Eszter A Janka1,2, Patrícia Ari1
1Department of Dermatology, MTA Centre of Excellence, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
International Journal of Dermatology
|April 12, 2026
Summary
Chronic venous disease (CVD) is linked to obesity and inactivity. Modifying these risk factors, like weight and physical activity levels, may improve outcomes for patients with venous insufficiency.
Area of Science:
- Vascular Medicine
- Epidemiology
- Public Health
Background:
- Investigates risk factors associated with chronic venous disease (CVD).
- Compares prevalence of validated and unproven risk factors in CVD patients versus controls.
- Examines factors influencing CVD severity.
Purpose of the Study:
- To identify and compare risk factors in individuals with and without chronic venous disease (CVD).
- To determine factors contributing to the severity of chronic venous disease.
Main Methods:
- Utilized questionnaires for risk factors, anthropometrics, and medical history.
- Included 209 CVD patients and 194 controls.
- Assessed disease severity using the Venous Clinical Severity Score and CEAP classification.
Main Results:
- Regular exercise was more common in controls; prolonged sitting/standing was more prevalent in CVD patients.
- CVD patients exhibited higher rates of obesity and hypertension.
- Factors associated with severe CVD included prior deep vein thrombosis, obesity, prolonged sitting/standing, inactivity, and family history of varicose veins.
Conclusions:
- Modifiable risk factors such as weight and physical inactivity strongly correlate with severe chronic venous disease (CVD).
- Targeting and modifying these factors holds potential for improving CVD patient outcomes.
- Early identification of risk factors is crucial for effective management of venous insufficiency.
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