Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Archaeal Cell Wall01:29

Archaeal Cell Wall

1.7K
Archaeal cell walls are structurally and compositionally distinct from their bacterial counterparts, lacking the characteristic peptidoglycan layer found in most bacteria. Instead, archaeal cell walls exhibit remarkable diversity, utilizing materials such as pseudomurein, polysaccharides, and proteins to construct their protective outer layers. This structural flexibility is closely tied to archaea's ecological adaptability.S-Layers: The Common Archaeal Cell WallThe S-layer is the most...
1.7K
Bacterial Cell Wall01:22

Bacterial Cell Wall

5.5K
The bacterial cell wall is an essential structural component that encases the plasma membrane, preserving cellular integrity, determining shape, and protecting against osmotic stress. This rigid yet flexible structure primarily comprises peptidoglycan, a polymer that forms a mesh-like matrix conferring mechanical strength and flexibility.Peptidoglycan Composition and StructurePeptidoglycan, the core of the bacterial cell wall, comprises alternating units of N-acetylglucosamine (NAG) and...
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

On-Cell Detection of Polysaccharide One-Bond <sup>1</sup>J<sub>CH</sub> Couplings by Proton-Detected Solid-State NMR.

Journal of the American Chemical Society·2026
Same author

Host-membrane lipid composition controls <i>Cryptococcus neoformans</i> cellular targets.

Frontiers in immunology·2026
Same author

Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential.

Virulence·2025
Same author

Antifungal Innate Immunity.

Advances in experimental medicine and biology·2025
Same author

Rho2 regulates granulocyte-triggered stress adaptation and cell wall remodeling in Aspergillus fumigatus.

Microbiological research·2025
Same author

Molecular Distinction of Cell Wall and Capsular Polysaccharides in Encapsulated Pathogens by In Situ Magic-Angle Spinning NMR Techniques.

Journal of the American Chemical Society·2025

Related Experiment Video

Updated: Apr 14, 2026

Double-Staining Method to Detect Pectin in Plant-Fungus Interaction
06:39

Double-Staining Method to Detect Pectin in Plant-Fungus Interaction

Published on: February 4, 2022

5.4K

Aspergillus fumigatus Cell Wall: Current Advances in Structural Elucidation Methods.

Chaithanya Shetty1, Melba Elizabeth-Biju1, Vishukumar Aimanianda1

  • 1Department of Biochemistry, Kasturba Medical College Manipal, Manipal Academy of Higher Education (MAHE), Manipal, India.

Methods in Molecular Biology (Clifton, N.J.)
|April 12, 2026
PubMed
Summary

The fungal cell wall (CW) is vital for pathogenic fungi like Aspergillus fumigatus. Understanding its structure is key to developing new antifungal drugs and improving host immune defense against aspergillosis.

Keywords:
Aspergillus fumigatusConidiaHydrophobinsMelaninMyceliaPolysaccharides

More Related Videos

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
09:37

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

8.0K
Application of Membrane and Cell Wall Selective Fluorescent Dyes for Live-Cell Imaging of Filamentous Fungi
07:44

Application of Membrane and Cell Wall Selective Fluorescent Dyes for Live-Cell Imaging of Filamentous Fungi

Published on: November 28, 2019

24.0K

Related Experiment Videos

Last Updated: Apr 14, 2026

Double-Staining Method to Detect Pectin in Plant-Fungus Interaction
06:39

Double-Staining Method to Detect Pectin in Plant-Fungus Interaction

Published on: February 4, 2022

5.4K
Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR
09:37

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

8.0K
Application of Membrane and Cell Wall Selective Fluorescent Dyes for Live-Cell Imaging of Filamentous Fungi
07:44

Application of Membrane and Cell Wall Selective Fluorescent Dyes for Live-Cell Imaging of Filamentous Fungi

Published on: November 28, 2019

24.0K

Area of Science:

  • Mycology
  • Immunology
  • Drug Discovery

Background:

  • The fungal cell wall (CW) is an essential extracellular organelle providing structural integrity and environmental protection.
  • In pathogenic fungi, the CW is a target for antifungal drug development and crucial for understanding host-pathogen interactions.
  • Aspergillus fumigatus, an airborne pathogen, causes various forms of aspergillosis, particularly in individuals with underlying lung conditions or compromised immunity.

Purpose of the Study:

  • To investigate the dynamic organization and molecular composition of the Aspergillus fumigatus cell wall.
  • To identify strategies for developing novel antifungal molecules targeting the fungal CW.
  • To enhance understanding of host immune system interactions with the fungal CW for improved aspergillosis management.

Main Methods:

  • Protocols for extracting diverse cell wall components from Aspergillus fumigatus.
  • Methods for quantifying extracted cell wall components.
  • Techniques for analyzing the structural organization of the Aspergillus fumigatus cell wall at a molecular level.

Main Results:

  • The study provides a compilation of essential protocols for detailed cell wall analysis.
  • Established methods allow for the characterization of cell wall composition and structure.
  • These techniques are crucial for understanding how Aspergillus fumigatus adapts and evades host defenses.

Conclusions:

  • Deciphering the Aspergillus fumigatus cell wall's dynamic organization is critical for effective antifungal strategies.
  • This research facilitates the development of new treatments against aspergillosis by targeting the fungal cell wall.
  • Understanding cell wall structure aids in improving host immune responses against fungal infections.