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Related Concept Videos

Burn Injuries01:22

Burn Injuries

5.0K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
5.0K

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Author Spotlight: A Multi-Depth Porcine Model for Comprehensive Study of Burn Injuries and Healing Processes
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Stroke After Burn: A Scoping Review.

Grant Gerstner1, Kyle Smiley1, David Lidwell2

  • 1Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, TX 78234, United States.

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|April 12, 2026
PubMed
Summary

Patients with burn injuries face increased risks of stroke, a serious cerebrovascular accident. This review synthesizes limited studies, highlighting a need for more research on burn-related stroke incidence and management.

Keywords:
CVAburncerebrovascular accidentstroke

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Area of Science:

  • Medical research
  • Vascular health
  • Burn injury outcomes

Background:

  • Burn injuries are linked to vascular issues like endothelial dysfunction and hypercoagulability, which are also stroke risk factors.
  • Limited research exists on the specific risk of cerebrovascular accidents (strokes) following cutaneous burn injuries.
  • Understanding this risk is crucial for patient management and preventative strategies.

Purpose of the Study:

  • To systematically review and synthesize existing literature on cerebrovascular accidents occurring after cutaneous burn injuries.
  • To identify the current evidence base regarding the incidence and risk factors of stroke post-burn.
  • To highlight gaps in the research, particularly concerning applicability to diverse populations.

Main Methods:

  • A comprehensive scoping review was conducted using PubMed Medline, Ovid Medline, and Cochrane databases.
  • Searches focused on identifying studies reporting stroke after burn injuries in titles and abstracts.
  • Twelve studies, including cohort/observational studies and case reports/series, met the final inclusion criteria.

Main Results:

  • Most included studies indicated an elevated incidence or hazard ratio of stroke following burn injury.
  • Significant heterogeneity among studies limited direct comparative analysis of stroke risk.
  • A notable gap was identified, as none of the included studies originated from the United States.

Conclusions:

  • The available literature suggests a potential increased risk of stroke after burn injury, but evidence is limited and heterogeneous.
  • Further research is essential to accurately determine the risk of stroke post-burn and to inform clinical management strategies.
  • Addressing the geographical gap in research is critical for broader applicability of findings.