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Updated: Apr 14, 2026

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
Published on: June 13, 2025
Endoscopic ultrasound-guided coil embolization and absorbable hemostatic gelatin sponge is a safe and efficacious
Kanwal Bains1,2, Thomas J Wang1,3, Marvin Ryou1
1Division of Gastroenterology and Hepatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Background And Aims:
Rectal variceal bleeding is a rare life-threatening cause of lower gastrointestinal bleeding. We present the first case series to our knowledge of successful hemostasis achieved with combination of endoscopic ultrasound (EUS)-guided coil embolization and absorbable gelatin sponge (AGS) for bleeding rectal varices.
Methods:
We performed a retrospective review of 6 patients with active rectal variceal bleeding. All patients underwent EUS-guided coil embolization with AGS therapy. Procedural details, technical success, adverse events, and rebleeding rates were measured.
Results:
We achieved 100% technical success (6 of 6 patients) with successful sonographic rectal varices decompression. A range of 1 to 4 coils with a total length of 7 to 20 cm was injected along with AGS. There were no adverse events or rebleeding from recurrent rectal varices. Median follow-up period was 190 days.
Conclusions:
EUS-guided coiling coupled with AGS therapy appears to be a potentially safe and efficacious alternative for patients with bleeding rectal varices.
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