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Moderate-Dose Local Radiotherapy in Symptomatic CD30-Positive, Anaplastic Lymphoma Kinase (ALK)-Negative Primary
Alejandra Varela1, Sebastián Sepúlveda1, Nicole E Evans1
1Faculty of Medicine, Universidad de Panamá, Panama, PAN.
Cureus
|April 13, 2026
Summary
Localized radiotherapy effectively managed a patient with refractory cutaneous CD30-positive T-cell lymphoma. This treatment reduced symptoms and controlled disease progression in an ulcerated lesion.
Area of Science:
- Oncology
- Dermatology
- Hematology
Background:
- Primary cutaneous anaplastic CD30-positive T-cell lymphoma (PC-aCD30+ TCL) is a rare skin cancer.
- It presents as rapidly growing, ulcerating nodules but often has a good prognosis in early stages.
- Radiotherapy is a known treatment, but data on low-dose efficacy is limited.
Keywords:
alk-negativecase reportcd30-positive t-cell lymphomaprimary cutaneous t-cell lymphomaradiation oncologyradiotherapyMore Related Videos
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