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Precision management of severe coronary artery calcification with concomitant left ventricular outflow tract

Wei Qi1,2, Yazheng Zhang3,4, Zhenzhen Wang5

  • 1Department of Cardiology, Tianjin Chest Hospital, Tianjin, China.

Frontiers in Medicine
|April 13, 2026
PubMed

Insights

Severe coronary artery calcification with hypertrophic cardiomyopathy and outflow tract obstruction is challenging. Multimodal management effectively relieved symptoms and obstruction in a complex case.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiovascular Imaging

Background:

  • Severe coronary artery calcification (CAC) poses diagnostic and therapeutic challenges, especially when combined with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract obstruction (LVOTO).
  • This case highlights the complexity of managing patients with coexisting severe CAC, HCM, and dynamic LVOTO.
Abstract

Keywords:
CACHCMIVUSLVOTOQFRmavacamten

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