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Recurrent Extranodal Diffuse Large B-Cell Lymphoma Manifesting as a Cecal Mass Over 10 Years After Remission
Jyoti Yadav1, Yeshika Thapa2, John Horne3
1Department of Internal Medicine, The Wright Center for Graduate Medical Education, Scranton, PA.
ACG Case Reports Journal
|April 13, 2026
Summary
A rare case of diffuse large B-cell lymphoma (DLBCL) relapsed over 10 years post-treatment, presenting as a cecal mass. This highlights the need for vigilance in elderly patients with unusual GI and urinary symptoms.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Diffuse large B-cell lymphoma (DLBCL) commonly affects extranodal sites, particularly the gastrointestinal tract.
- Very late relapse of DLBCL after long-term remission and predominant colorectal involvement are rare occurrences.
- Extranodal DLBCL relapse requires consideration in elderly patients presenting with atypical gastrointestinal and urinary symptoms.
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