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Advanced practice providers (APPs) can now safely write anti-cancer therapy orders for clinical trial patients, aligning with National Cancer Institute (NCI) guidance. This expansion supports APP autonomy and engagement in cancer research.

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Area of Science:

  • Oncology
  • Clinical Research
  • Healthcare Policy

Background:

  • The National Cancer Institute (NCI) updated policies in September 2021 to allow advanced practice providers (APPs) greater autonomy.
  • This change permits APPs to write orders for research-related anti-cancer therapies, enhancing their role in clinical trials.

Purpose of the Study:

  • To implement and assess a process for enabling APPs to independently write non-Cycle 1 Day 1 study agent orders.
  • To ensure compliance with NCI guidance and maintain safety and credentialing standards.

Main Methods:

  • An academic institution revised health-system policies to incorporate APP order-writing capabilities.
  • Established a tracking system for NCI Registration and Credentialing Roster (RCR) expirations and an audit process for order verification.

Main Results:

  • No adverse comments received from accrediting or supporting organizations regarding APP order-writing for anti-cancer trials.
  • No instances of APPs losing prescribing privileges due to RCR non-renewal were reported.

Conclusions:

  • Advanced practice providers can safely and effectively write anti-cancer treatment orders for patients in clinical trials.
  • Empowering APPs in this capacity may increase their involvement and contribution to research initiatives.