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Delayed Care in Self-Presenting Stroke Patients: Real-World Data on Process Delays-Comparing Process Times Between
Christian Claudi1,2, Patrick Schramm1,3, Martin Juenemann1
1Department of Neurology, University Hospital Giessen, 35392 Giessen, Germany.
Journal of Clinical Medicine
|April 14, 2026
Summary
Self-presenting stroke patients face longer prehospital delays and lower rates of intravenous thrombolysis compared to those using Emergency Medical Services (EMS). Public education is crucial for timely EMS activation in stroke emergencies.
Area of Science:
- Neurology
- Emergency Medicine
- Public Health
Background:
- Stroke is a time-critical medical emergency requiring rapid diagnosis and treatment.
- Emergency Medical Services (EMS) streamline prehospital stroke care.
- Self-presentation to emergency departments bypasses EMS, potentially delaying critical treatment.
Purpose of the Study:
- To compare prehospital and in-hospital process times between EMS-transported and self-presenting stroke patients.
- To evaluate treatment outcomes, specifically intravenous thrombolysis (IVT) rates, in both patient groups.
Main Methods:
- Retrospective analysis of prospectively collected data from 1805 suspected stroke patients admitted between May 2019 and June 2021.
- Patients categorized into EMS-transported and self-presenting groups.
- Key metrics: door-to-needle time (DNT), symptom onset to first medical contact (FMC), and IVT rates.
Main Results:
- Self-presenting patients had significantly longer median onset-to-first-contact times (727 min vs. 114 min for EMS patients).
- Intravenous thrombolysis (IVT) rates were 9.9% for EMS patients and 7.1% for self-presenting patients (not statistically significant).
- In-hospital door-to-needle times were slightly longer for self-presenting patients (median 35 min vs. 30 min for EMS patients) but within targets.
Conclusions:
- Self-presenting stroke patients experience substantial prehospital delays and tend to have lower IVT rates.
- In-hospital treatment times were comparable, indicating efficient emergency department care.
- Enhanced public education is vital to promote rapid recognition of stroke symptoms and encourage timely EMS activation.
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