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The Effectiveness of Virtual Reality-Based Interventions in Patients with Ataxic Conditions: A Systematic Review with
Marina Piñar-Lara1,2, Ana González-Carmona1, Esteban Obrero-Gaitán1
1Department of Health Sciences, University of Jaén, Campus Las Lagunillas s/n, 23071 Jaén, Spain.
Sensors (Basel, Switzerland)
|April 14, 2026
Summary
Virtual reality-based interventions (VRBIs) effectively reduce ataxia severity and improve balance and manual dexterity in patients. This therapy shows promise for managing ataxia symptoms and enhancing patient function.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Human-Computer Interaction
Background:
- Ataxic symptoms manifest as motor, balance, and coordination impairments.
- Virtual reality-based interventions (VRBIs), including video games and exergames, show potential for improving ataxic symptoms.
Purpose of the Study:
- To systematically review and meta-analyze the effectiveness of VRBI on ataxia severity, postural balance, mobility, and manual dexterity in patients with ataxia.
Main Methods:
- A systematic review and meta-analysis adhering to PRISMA guidelines.
- Searched multiple databases (PubMed, SCOPUS, WOS, CINAHL, PEDro) for relevant randomized controlled trials (RCTs).
- Pooled effect calculated using Cohen's standardized mean difference (SMD) with 95% confidence intervals.
Main Results:
- Analysis of seven RCTs involving 171 patients with ataxia.
- VRBI significantly reduced ataxia severity (SMD = -0.43, p=0.04).
- VRBI improved functional balance (SMD = 0.97, p=0.02) and manual dexterity (SMD = -0.63, p=0.018).
Conclusions:
- VRBI presents a promising therapeutic strategy for ataxic patients.
- The intervention effectively reduces ataxia-related disability.
- VRBI enhances balance and manual dexterity in individuals with ataxia.
