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Related Concept Videos

Olfaction01:25

Olfaction

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
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Physiology of Smell and Olfactory Pathway01:20

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Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
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Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

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The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
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A Novel Artificial Intelligence-Enabled Method for Electronic Nose Design Based on Olfactometry Data.

Gizem Teker1,2, Taner Yonar2,3, Enes Yiğit1

  • 1Faculty of Electrical and Electronics Engineering, Bursa Uludag University, Bursa 16059, Türkiye.

Sensors (Basel, Switzerland)
|April 14, 2026
PubMed
Summary
This summary is machine-generated.

Electronic nose technology offers objective odor evaluation by mimicking human olfaction. This study validates its reliability using a standardized reference odor and machine learning, showing high predictive accuracy.

Keywords:
TS EN 13725electronic nosemachine learningmetal oxide sensorsn-butanolodor quantificationolfactometry

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Area of Science:

  • Analytical Chemistry
  • Sensor Technology
  • Biomimicry

Background:

  • Electronic nose (e-nose) systems objectively evaluate odors using sensor arrays and data processing.
  • They offer rapid, reproducible, and standardized chemical measurements for various industries.
  • Applications span food safety, environmental monitoring, medical diagnostics, and industrial quality control.

Purpose of the Study:

  • To compare electronic nose sensor measurements with human olfactometry panelist assessments.
  • To evaluate the predictive accuracy of machine learning algorithms for e-nose data.
  • To validate the performance of e-nose technology using a standardized reference odor (n-butanol) and TS EN 13725 standard.

Main Methods:

  • Measurements from e-nose sensors were compared against human panelist assessments.
  • Machine learning algorithms including Partial Least Squares (PLS), Support Vector Regression (SVR), and Gaussian Process Regression (GPR) were employed.
  • Data modeling and predictive accuracy evaluation were performed using these algorithms.

Main Results:

  • The electronic nose system demonstrated reliability and applicability in odor assessment.
  • Machine learning models achieved low training Mean Absolute Percentage Error (MAPE) values: 6.53% for PLS, 10.89% for SVR, and 0.15% for GPR.
  • Gaussian Process Regression (GPR) showed particularly high predictive accuracy.

Conclusions:

  • The study successfully assessed the performance of electronic nose technology.
  • The use of a standardized reference odor and robust modeling approach confirmed the system's effectiveness.
  • Electronic nose technology, enhanced by machine learning, provides a reliable method for objective odor analysis.