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Calorimetry

Calorimetry

When objects at different temperatures are placed in contact with each other but isolated from everything else, they attain thermal equilibrium. A container that prevents heat transfer in or out is called a calorimeter, and the use of a calorimeter to make measurements is called calorimetry. Generally, these measurements involve heat or specific heat capacity. The term "calorimetry problem" is used for any problem where the specified objects are thermally isolated from their...

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Related Experiment Video

Updated: Apr 15, 2026

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism

Calorespirometry: A Powerful, Noninvasive Approach to Investigate Cellular Energy Metabolism

Published on: May 31, 2018

Chip Calorimetry for Single-Cell Analysis: Advances, Challenges, and Opportunities.

Yara Abdelaal¹, Luis Guillermo Villanueva¹

¹Advanced NEMS Laboratory, École Polytechnique Fédérale de Lausanne (EPFL), Route Cantonale, 1015 Lausanne, Switzerland.

Sensors (Basel, Switzerland)

|April 14, 2026

Summary

Chip calorimetry offers powerful insights into biological processes and healthcare by measuring heat changes. This review details advances, applications, and challenges in miniaturized thermal measurement technology.

Keywords:

MEMS bimaterial cantilever differential scanning calorimetry isothermal titration calorimetry microresonators photothermal biosensing resistive temperature detector thermistor thermocouple thermopile

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Last Updated: Apr 15, 2026

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Area of Science:

Biotechnology
Biophysics
Analytical Chemistry

Background:

Heat changes are vital in biological processes, impacting metabolism, biomolecular interactions, and cell studies.
Thermal measurements offer potential in healthcare for drug susceptibility testing and disease diagnosis.
Advances in micro- and nanofabrication have driven the development of chip calorimeters.

Purpose of the Study:

To provide a comprehensive review of significant advances in chip calorimetry.
To discuss the figures of merit, applications, and challenges associated with chip calorimeters.
To highlight the current state-of-the-art and future prospects in the field.

Main Methods:

Review of recent literature on chip calorimetry.
Analysis of key performance metrics (figures of merit).
Categorization and discussion of diverse applications.

Main Results:

Significant progress has been made in miniaturizing calorimetry.
Chip calorimeters demonstrate broad applicability across biological and healthcare fields.
Key challenges and areas for future development have been identified.

Conclusions:

Chip calorimetry represents a rapidly evolving field with substantial potential.
Further innovation is expected in sensor technology, fabrication, and data analysis.
This technology promises to enhance our understanding and monitoring of biological systems.