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Peripheral Intravenous Catheters in Hospitalized Surgical Patients: A US Real-World Data Analysis.
Rena Moon1, Julie Gayle1, Stephanie Pitts2
1Premier Applied Sciences, Premier Inc., Charlotte, North Carolina.
Journal of Health Economics and Outcomes Research
|April 14, 2026
Summary
Peripheral intravenous catheter (PIVC)-associated complications in surgical patients significantly increase hospitalization costs, length of stay, and readmission risks. Addressing these PIVC complications is crucial for improving patient outcomes and reducing healthcare burdens.
Area of Science:
- Medical Economics
- Patient Safety
- Health Services Research
Background:
- Limited data exists on the clinical and economic impact of peripheral intravenous catheter (PIVC)-associated complications in hospitalized surgical patients.
- Understanding these burdens is essential for developing targeted interventions.
Purpose of the Study:
- To estimate the prevalence of PIVC-associated complications in adult and pediatric surgical inpatients.
- To compare healthcare resource utilization and associated costs between patients with and without PIVC complications.
Main Methods:
- A retrospective cohort study analyzed a large US hospital database (Premier Healthcare Database) from January 1, 2019, to December 31, 2023.
- Included were adult and pediatric surgical patients without central line access.
Main Results:
- In adults (N=6,992,120), PIVC complication prevalence was 0.7%, associated with a 46% higher readmission risk, 5.52 days longer LOS, and $19,074 increased cost.
- In pediatrics (N=159,256), prevalence was 0.5%, linked to a 115% higher 30-day readmission risk, 4.50 days longer LOS, and $16,052 increased cost.
Conclusions:
- PIVC-associated complications significantly elevate hospitalization costs, length of stay, and 30-day readmission rates in both adult and pediatric surgical patients.
- These findings underscore the need for stakeholders to implement strategies to mitigate PIVC complications.
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