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Updated: Apr 15, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Thrombus Formation During Pulmonary Vein Ablation: When Routine Turns Risky
Álvaro Barranco de Santiago1, Mireia Pozo-Albiol1, Samira Martínez-Otero1
1Department of Anesthesiology and Critical Care, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain.
Intraprocedural catheter thrombosis during atrial fibrillation ablation is rare but serious. Early detection with intraoperative transesophageal echocardiography (iTEE) and uninterrupted anticoagulation are crucial for patient safety.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Electrophysiology
Background:
- Atrial fibrillation (AF) is a common arrhythmia linked to thromboembolic events.
- Pulmonary vein isolation is a primary treatment for AF rhythm control.
- Intraoperative transesophageal echocardiography (iTEE) aids procedural safety in AF ablation.
Purpose of the Study:
- To report a rare case of intraprocedural catheter thrombosis during AF ablation.
- To highlight the role of iTEE in detecting this complication.
- To emphasize the importance of anticoagulation management in AF ablation.
Main Methods:
- A case report of a 59-year-old male patient with paroxysmal AF undergoing redo pulmonary vein ablation.
- Utilized iTEE for procedural guidance and complication surveillance.
- Managed anticoagulation status, including interruption and subsequent uninterrupted use.
Main Results:
- iTEE identified a large thrombus on the ablation catheter after transseptal puncture due to interrupted anticoagulation.
- Procedure was postponed, and the patient recovered without complications.
- Successful redo ablation was performed 4 weeks later under uninterrupted anticoagulation.
Conclusions:
- Intraprocedural catheter thrombosis is a rare, potentially life-threatening complication of AF ablation.
- iTEE is vital for early detection and procedural guidance.
- Uninterrupted anticoagulation is essential for mitigating thromboembolic risk during AF ablation.
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