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Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures.

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Area of Science:

  • Otolaryngology
  • Pain Management
  • Public Health

Background:

  • Perioperative opioid use is common for otolaryngological procedures.
  • The development of new persistent opioid use following these surgeries is not well understood.

Purpose of the Study:

  • To evaluate the incidence of perioperative opioid prescription.
  • To assess the development of new persistent opioid use in patients undergoing common otolaryngological procedures.

Main Methods:

  • Retrospective cohort study using the TriNetX US Collaborative Research Network.
  • Identified opioid-naive adult patients undergoing specific otolaryngological procedures (2010-2024).
  • Propensity score matching was used to compare patients who received perioperative opioids versus those who did not, controlling for various demographic and clinical factors.

Main Results:

  • Over 319,000 patients were analyzed, with 85.8% receiving perioperative opioids.
  • Patients receiving perioperative opioids had a higher likelihood of developing new persistent opioid use.
  • Parotidectomy and tympanoplasty showed the highest risk ratios for new persistent opioid use.

Conclusions:

  • Perioperative opioid prescribing after otolaryngological surgery is linked to an increased risk of new persistent opioid use.
  • Findings underscore the importance of judicious opioid prescribing practices.
  • Reducing long-term opioid dependence requires careful management of perioperative pain medication.