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Updated: Apr 17, 2026

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Assessment of Human Natural Killer Cell Events Driven by FcγRIIIa Engagement in the Presence of Therapeutic Antibodies
Published on: May 22, 2020
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Minimal Change Nephrotic Syndrome Complicated by Classical Hodgkin Lymphoma During Prolonged Rituximab Maintenance
Koshi Yamada1, Mayu Kijiya1, Takeo Koshida1
1Department of Nephrology, Juntendo University Faculty of Medicine, Tokyo, Japan.
Nephrology (Carlton, Vic.)
|April 16, 2026
Summary
Minimal change nephrotic syndrome (MCNS) relapse is linked to B-cell dysfunction. A rare case shows classical Hodgkin lymphoma (cHL) developing during rituximab (RTX) therapy, highlighting the need for safety monitoring during B-cell depletion.
Area of Science:
- Nephrology
- Hematology
- Immunology
Background:
- Minimal change nephrotic syndrome (MCNS) is increasingly linked to B-cell involvement.
- Rituximab (RTX), a B-cell depleting therapy, is used for MCNS maintenance, but its long-term safety is not fully understood.
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