Related Experiment Video
Updated: Apr 17, 2026
06:32
A Chitosan Based, Laser Activated Thin Film Surgical Adhesive, 'SurgiLux': Preparation and Demonstration
Published on: October 23, 2012
13.8K
Cyanoacrylate Adhesive With Low-Level Laser Therapy for Sutureless Periodontal Flap Closure: A Pilot Randomized
Kratee Sharma1, Shalabh Mehrotra1
1Department of Periodontics, Teerthanker Mahaveer Dental College and Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.
Lasers in Surgery and Medicine
|April 16, 2026
Summary
A sutureless periodontal flap closure using cyanoacrylate adhesive and low-level laser therapy (LLLT) reduced pain and analgesic use compared to conventional sutures. This pilot study suggests improved early outcomes for this novel approach in periodontal surgery.
Area of Science:
- Periodontal Surgery
- Biomaterials
- Laser Therapy
Background:
- Conventional suturing in periodontal flap surgery can cause discomfort and requires follow-up visits for removal.
- Cyanoacrylate tissue adhesives and low-level laser therapy (LLLT) have individually demonstrated benefits in wound healing and reducing postoperative symptoms.
Purpose of the Study:
- To evaluate the feasibility and preliminary clinical outcomes of a sutureless periodontal flap closure technique.
- To compare cyanoacrylate adhesive with adjunctive LLLT against conventional suturing for periodontal flap surgery.
Main Methods:
- A pilot randomized controlled trial involving 20 adults with periodontitis undergoing flap surgery.
- Participants were randomized to receive either conventional silk sutures or cyanoacrylate adhesive with LLLT.
- Primary outcome was postoperative pain (visual analog scale); secondary outcomes included wound healing, analgesic consumption, and clinical periodontal parameters.
Main Results:
- The cyanoacrylate adhesive with LLLT group showed significantly lower analgesic consumption and higher patient preference.
- Postoperative pain scores were consistently lower, and early wound healing scores were higher in the intervention group.
- Both groups achieved significant reductions in probing pocket depth and clinical attachment level, with no significant between-group differences.
Conclusions:
- Cyanoacrylate adhesive combined with LLLT appears to be a feasible sutureless technique for periodontal flap closure.
- This approach may enhance early postoperative outcomes, including reduced pain and improved healing.
- Larger randomized trials are needed to validate these promising preliminary findings.
