[Delayed post-hypoxic leukoencephalopathy as a cause of neuropsychiatric symptoms]

A 50-year-old woman developed delayed post-hypoxic leukoencephalopathy with severe cognitive and behavioural symptoms a month after hypoxic injury, with subsequent slow recovery and radiological improvement. DPHL is a rare neurological syndrome that develops days to weeks after cerebral hypoxia. Patients often show neuropsychiatric symptoms. MRI usually shows white matter changes. There is no specific treatment, but most improve gradually with neurorehabilitation. This case report highlights the challenge of diagnosing DPHL in patients with new neuropsychiatric symptoms following hypoxic events.