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Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
Published on: August 6, 2019
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Polyethyleneimine-functionalized MXene as stable two-dimensional platforms for gene delivery systems
Farhan Hadi1, Seoyeon Park2, Tae-Il Kim2,3
1Department of Energy & Materials Engineering, Dongguk University, Seoul, 04620, Republic of Korea. jaemin.oh@dongguk.edu.
Abstract:
This study examined the influence of polyethyleneimine (PEI) molecular weight on the chemical bonding, colloidal behavior, pDNA loading, cytotoxicity, and cellular uptake of PEI-MXene hybrids. The hybrids showed reduced cytotoxicity compared with PEI, highlighting their potential as safe pDNA delivery systems.

