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Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...

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Updated: Apr 19, 2026

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes

High-throughput Screening for Chemical Modulators of Post-transcriptionally Regulated Genes

Published on: March 3, 2015

AI-derived constrained conditional model for screening marker genes through integrated high-throughput transcriptome

Xiaobei Zhou¹, Jing Wan¹, Na Lv¹

¹Key Laboratory of Obesity and Glucose/Lipid Associated Metabolic Diseases, Institute of Health Sciences, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, 110122, China.

BMC Medical Research Methodology

|April 17, 2026

Summary

No abstract available in PubMed .

Keywords:

Bootstrapping Constraints Differential gene Marker genes Transcriptome data

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