Related Experiment Video
Updated: Apr 20, 2026

Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development
Published on: March 5, 2017
Created, Not Engineered: Analyzing Human Gene Editing from a Catholic Anthropological and Moral Perspective
Francheska Lhiane D Igama1, Francis Raphael G Lavapie1, Rafael Sebastian G Ng1
1College of Nursing, University of Santo Tomas, Manila, Philippines.
The Catholic Church evaluates human gene editing based on dignity and integrity. It supports therapeutic uses but rejects genetic manipulation that engineers human nature, advocating for ethical boundaries in biotechnology.
Area of Science:
- Bioethics
- Theology
- Human Genetics
Background:
- Advances in human gene editing present ethical challenges to the Catholic Church's view of human dignity.
- Germline modifications, in particular, require careful moral evaluation within established theological principles.
Purpose of the Study:
- To examine the Catholic Church's moral evaluation of human gene editing, especially germline modifications.
- To apply the Catholic moral framework, using the See-Judge-Act model, to contemporary gene editing technologies.
- To assess whether gene editing interventions respect or compromise inherent human dignity.
Main Methods:
- Doctrinal and hermeneutical analysis of Catholic moral teachings.
- Application of foundational principles: human dignity, imago Dei, solidarity, and responsible care.
- Utilizing the See-Judge-Act model for ethical assessment.
Main Results:
- Gene editing technologies, primarily for genetic diseases, are evaluated against Catholic ethical principles.
- The Church's framework emphasizes respecting human dignity and integrity, distinguishing therapy from unacceptable alteration.
- A future-oriented view is necessary to address both therapeutic and enhancement applications of gene editing.
Conclusions:
- The Catholic Church's ethical response to gene editing prioritizes human dignity and rejects engineering human nature.
- Ethical boundaries are crucial to differentiate legitimate therapeutic interventions from unacceptable alterations.
- A Christian ethical approach must anticipate future biotechnologies while upholding the sanctity of human life.
Related Concept Videos
What is Genetic Engineering?
CRISPR
Animal Mitochondrial Genetics
The Central Dogma
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
Homologous Recombination
CRISPR/Cas9 Genome Editing

