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Updated: Apr 21, 2026

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Multimodal Artificial Intelligence for Precision Critical Care: A Scoping Review.

Meicheng Yang1, Nan Shi2, Hui Chen2

  • 1School of Nursing, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.

Health Data Science
|April 20, 2026
PubMed
Summary

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This summary is machine-generated.

Multimodal artificial intelligence (AI) integrating diverse patient data shows promise for critical care. This review highlights AI

Area of Science:

  • Critical care medicine
  • Artificial intelligence
  • Data science

Background:

  • Intensive care units (ICUs) generate vast, complex patient data.
  • Multimodal artificial intelligence (AI) offers potential for precision medicine in critical care.
  • Comprehensive reviews on multimodal AI in ICUs are limited.

Purpose of the Study:

  • To systematically review the progress, methods, and challenges of multimodal AI in critical care.
  • To provide a roadmap for developing and implementing multimodal AI in ICUs.

Main Methods:

  • Scoping review following PRISMA-ScR guidelines.
  • Systematic literature search across major databases (PubMed, EMBASE, Scopus, Web of Science, IEEE Xplore) from 2010-2025.
  • Inclusion of studies integrating at least two data modalities using AI for critical care outcomes.

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Main Results:

  • 86 studies included, 85% published in the last 5 years.
  • Common modalities: structured data, text, imaging, waveforms, videos.
  • Intermediate fusion was the primary integration strategy.
  • Multimodal AI achieved a 4.4% relative improvement in AUC for diagnostic/prognostic tasks compared to unimodal models.

Conclusions:

  • Multimodal AI demonstrates superior performance in critical care tasks.
  • This review offers a strategic framework for multimodal AI design, evaluation, and implementation in the ICU.
  • The ultimate goal is to enhance patient outcomes through advanced AI integration.