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Study of Niobium-Based Coatings and Silver Incorporation for Biomedical Applications
Ana Elisa Dotta Maddalozzo1, Júlia Abdala2, Amanda Santi3
1Graduate Program in Materials Science and Engineering, University of Caxias do Sul, 95070-560 Caxias do Sul, Rio Grande do Sul, Brazil.
ACS Omega
|April 20, 2026
Summary
Niobium-based coatings with silver were developed for biomedical applications. These advanced coatings show excellent resistance to corrosion, wear, and bacterial growth, proving effective for medical devices.
Area of Science:
- Materials Science
- Biomedical Engineering
- Surface Engineering
Background:
- Surface engineering is crucial for improving material performance in demanding environments like the biomedical sector.
- Key challenges in biomedical applications include corrosion, wear, and microbial contamination.
- Niobium-based materials offer potential for biomedical coatings due to their properties.
Purpose of the Study:
- To develop and characterize niobium-based coatings incorporating silver for biomedical applications.
- To evaluate the physicochemical and biological properties of these novel coatings.
- To assess their efficacy in preventing biofilm formation and their cytotoxicity.
Main Methods:
- Magnetron sputtering was used to create niobium nitride (NbN) and niobium pentoxide (Nb2O5) coatings.
- Ion plating with silver ions was employed to modify the niobium-based films.
- Comprehensive characterization of physicochemical and biological properties was performed.
Main Results:
- The developed coatings exhibited promising physicochemical properties, including corrosion and wear resistance.
- The niobium-silver coatings demonstrated excellent biocompatibility and significant bactericidal activity.
- Effective prevention of biofilm formation was observed without any cytotoxic effects.
Conclusions:
- Surface engineering with niobium and silver is an effective strategy for biomedical applications.
- These coatings offer a sustainable solution to mitigate corrosion, wear, and microbial contamination.
- The findings support the potential of these coatings for use in medical devices and implants.

