Related Experiment Video
Updated: Apr 22, 2026
11:17
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
11.6K
Pharmacist-Delivered Comprehensive Medication Management in a Substance Use Disorder Inpatient Residential Treatment
Lucas Kosobuski1,2, Laura Palombi2,3, Keri Hager1,2
1Center for Alcohol & Drug Treatment, Welia Health, Mora, Minnesota, USA.
Journal of the American College of Clinical Pharmacy : JACCP
|April 20, 2026
Summary
Pharmacists providing Comprehensive Medication Management (CMM) resolved 72.4% of medication therapy problems for patients with Substance Use Disorders (SUD). However, inadequate payment hinders the financial viability of these vital CMM services.
Area of Science:
- Pharmacy Practice
- Pharmacotherapy
- Public Health
Background:
- Substance Use Disorders (SUD) present a significant public health challenge in the US.
- Novel interventions are crucial to mitigate the impact of SUD.
- Pharmacist-led Comprehensive Medication Management (CMM) offers innovative solutions within addiction treatment settings.
Purpose of the Study:
- To characterize the patient population at the Center for Alcohol and Drug Treatment (CADT).
- To identify and resolve medication therapy problems (MTPs) during the initial 12 months of CMM implementation.
- To discuss the expansion of CMM services in residential SUD treatment.
Main Methods:
- A prospective, observational, and descriptive study design was employed.
- Analysis focused on the impact of CMM services provided to residential patients.
- Data collected over a 12-month implementation period.
Main Results:
- CMM services were delivered to 165 patients across 295 visits.
- An average of 7.3 medications, 3.9 conditions, and 2 MTPs were assessed per encounter.
- A high MTP resolution rate of 72.4% was achieved, but financial viability was challenged by inadequate payment.
Conclusions:
- CMM expansion at CADT demonstrated a high MTP resolution rate, showcasing pharmacy's role in combating the SUD crisis.
- The study highlights CMM as an innovative approach in SUD treatment.
- Reimbursement for CMM services remains a significant barrier to widespread implementation and sustainability.
Related Concept Videos
01:28Drug Therapy
436
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
436
01:28Pulmonary Tuberculosis V
962
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
962
01:29Therapeutic Drug Monitoring: Affecting Factors
414
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
414
01:16Therapeutic Drug Monitoring: Overview and Classification
614
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
614
01:28Dosage Regimens: Designs and Approaches
589
Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
589
01:26Psychosis: Goals of Pharmacotherapy
686
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
686